硫糖铝（Sucralfate Suspensoid）是护胃剂[1]、补充剂，属于非神经药物。不可滥用。
硫糖铝在胃肠道吸收仅5%，作用持续时间约5小时[6]。主要随粪便排出，少量以双糖硫酸盐随尿排出[7]。
通过医生处方获取。
Sucralfate. A review of its pharmacodynamic properties and therapeutic use in peptic ulcer disease: "Sucralfate is a basic aluminium salt of sulphated sucrose which is advocated for use in peptic ulcer disease. It is minimally absorbed after oral administration and is believed to act primarily at the ulcer site by protecting the ulcer from the effects of pepsin, acid and possibly bile salts." ↩︎
硫糖铝是含有氢氧化铝的硫酸蔗糖复合物，在酸性条件下离解胃带负电荷的八硫酸蔗糖，能聚合成胶体直接在溃疡表面或炎症处形成一层薄膜，保护溃疡或炎症粘膜，抵御胃酸的侵袭。 ↩︎
来自说明书：此外，硫糖铝能吸附胃蛋白酶并中和胃酸，但作用弱。 ↩︎
Sucralfate. A review of its pharmacodynamic properties and therapeutic use in peptic ulcer disease:"Sucralfate is particularly well tolerated. Constipation, the most common side effect, occurs in 2% of patients." ↩︎
Sucralfate. A review of its pharmacodynamic properties and therapeutic use in peptic ulcer disease:"Controlled therapeutic trials have demonstrated that sucralfate 1g 4 times daily is effective in increasing the rate of healing of duodenal and gastric ulcer over a period of 4 to 8 weeks." ↩︎
Sucralfate - StatPearls - NCBI Bookshelf: "Absorption: Only 5% of an orally administered dose is absorbed. The onset of action is 1 to 2 hours. The drug's duration of action is up to 6 hours." ↩︎
Sucralfate: pharmacokinetics, metabolism and selective binding to experimental gastric and duodenal ulcers in animals："From the renal excretion data it is concluded that sucralfate is absorbed from the gastrointestinal tract of rat, Beagle dog, and Rhesus monkey only from 1% to 5% of the dose."
Clinical Drug-Drug Pharmacokinetic Interaction Potential of Sucralfate with Other Drugs: Review and Perspectives："Because sucralfate does not undergo any significant oral absorption, sucralfate resides in the GIT for a considerable length of time." ↩︎